Rotterdam Placenta Lab Departments of Neonatology & Pharmacology

Main placenta-related topics:

At the Erasmus MC Placenta Lab, we aim to dismantle placental alterations in pregnancy-related disorders and uncover new therapeutic targets to improve maternal, fetal and neonatal health.

For this, we explore the complexities of the placenta by taking a translational approach with a dedicated team of researchers and clinicians from the departments of Pharmacology, Neonatology, Obstetric Medicine, Pathology, and Pharmacy. Ultimately aiming for our results to go from ‘bench-to-bedside’ to improve outcomes for both mother and child.

We utilize various human placenta ex vivo models to study the transfer of (novel) drugs over the placenta as well as their effects on the placenta. A close collaboration between the departments of Neonatology, Pharmacology, Gynecology and Pathology allows us to execute this research with placentas from both uncomplicated as well as pathological pregnancies, estimating the safety and understanding the mechanisms of action of drugs in specifically those placentas that are aberrant.

Principal Investigators